The study presents the results from the use of tablets and an application having augmented reality features for teaching the digestive system to sixth-grade primary school students. For examining the above, three groups of students were formed. To the first, the teaching was conventional, the second group was taught using a collaborative teaching method, while the third was taught exclusively through the use of tablets. The teaching interventions lasted for three two-hour sessions (in each group) and, in total, 66 students were involved. Data were collected using evaluations sheets and a questionnaire. The results indicated that the group of students that was taught using tablets, outperformed the group that was taught conventionally and had equally good results with the group that was taught collaboratively. Also, students' views regarding the use of tablets were highly positive. Further studies are recommended and the implications are also discussed.